Signal-based liver eQTL meta-analysis (Broadaway et al. AJHG 2024)
Warning: To download the data, please copy the link address and use wget or curl in the terminal. Clicking on the link to download will not work. lternatively, the files can be downloaded from zenodo at the following link: Zenodo Broadaway et al. 2024. Contact Karen Mohlke (karen_mohlke@med.unc.edu) if you need help accessing the data.
Liver eQTL meta-analysis (Broadaway et al. AJHG 2024)
Below are the links for:
- Full marginal eQTL summary statistics
- Isolated conditional eQTL summary statistics
| Marginal eQTL summary stats: | |
| Column label | Description |
| Entrez | Entrez ID |
| Variant | Chromosome_position_NonEffectAllele_EffectAllele |
| CHR | Chromosome |
| POS | Position (hg19) |
| NEA | Non-effect allele |
| EA | Effect allele |
| EAF | Effect allele frequency |
| Beta | Effect size of association between variant and gene |
| SE | Standard error |
| PVAL | p-value of association between variant and gene |
| N | Sample size for variant |
| Studies | Studies with gene expressed. 1=Germany (145), 2=Schadt (555), 3=Merck (322), 4 = BLP (161) |
| GeneSymbol | Gene symbol: lookup biomaRt (version 2.50.3, Ensembl version 110) |
| ENSG | Ensembl ID for gene: lookup biomaRt (version 2.50.3, Ensembl version 110) |
| Gene_Biotype | Gene Biotype: lookup biomaRt (version 2.50.3, Ensembl version 110) |
| Files for download: | |
| Description | Marginal eQTL full summary statistics – all results by chromosome |
| Filename | Liver_eQTL_Meta_Marginal_20240530.tar.gz |
| Size | 1.9 GB |
| Date | 5/30/2024 |
| Isolated eQTL summary stats (each signal isolated): | |
| Column label | Description |
| GeneSymbol | Gene symbol: lookup biomaRt (version 2.50.3, Ensembl version 110) |
| Entrez | Entrez ID |
| SignalLead | Lead variant of isolated signal |
| Variant | Chromosome_position_NonEffectAllele_EffectAllele |
| NEA | Non-effect allele |
| EA | Effect allele |
| EAF | Effect allele frequency |
| Beta | Effect size of association between variant and gene |
| SE | Standard error |
| PVAL | p-value of association between variant and gene |
| N | Sample size for variant |
| Studies | Studies with gene expressed. 1=Germany (145), 2=Schadt (555), 3=Merck (322), 4 = BLP (161) |
| ENSG | Ensembl ID for gene: lookup biomaRt (version 2.50.3, Ensembl version 110) |
| Gene_Biotype | Gene Biotype: lookup biomaRt (version 2.50.3, Ensembl version 110) |
| Files for download: | Liver_eQTL_Meta_Isolated_20240530.tar.gz |
| Description | Isolated conditional summary statistics for signficant signals – all results by chromosome |
| Filename | |
| Size | 1.5 GB |
| Date | 5/30/2024 |