Signal-based liver eQTL meta-analysis (Broadaway et al. AJHG 2024)
Warning: To download the data, please copy the link address and use wget or curl in the terminal. Clicking on the link to download will not work. Contact Karen Mohlke (karen_mohlke@med.unc.edu) if you need help accessing the data.
Liver eQTL meta-analysis (Broadaway et al. AJHG 2024)
Below are the links for:
- Full marginal eQTL summary statistics
- Isolated conditional eQTL summary statistics
| Marginal eQTL summary stats: | |
| Column label | Description |
| Entrez | Entrez ID |
| Variant | Chromosome_position_NonEffectAllele_EffectAllele |
| CHR | Chromosome |
| POS | Position (hg19) |
| NEA | Non-effect allele |
| EA | Effect allele |
| EAF | Effect allele frequency |
| Beta | Effect size of association between variant and gene |
| SE | Standard error |
| PVAL | p-value of association between variant and gene |
| N | Sample size for variant |
| Studies | Studies with gene expressed. 1=Germany (145), 2=Schadt (555), 3=Merck (322), 4 = BLP (161) |
| GeneSymbol | Gene symbol: lookup biomaRt (version 2.50.3, Ensembl version 110) |
| ENSG | Ensembl ID for gene: lookup biomaRt (version 2.50.3, Ensembl version 110) |
| Gene_Biotype | Gene Biotype: lookup biomaRt (version 2.50.3, Ensembl version 110) |
| Files for download: | |
| Description | Marginal eQTL full summary statistics – all results by chromosome |
| Filename | Liver_eQTL_MarginalResults_byChr.tar.gz |
| Size | 1.9 GB |
| Date | 3/4/24 |
| Isolated eQTL summary stats (each signal isolated): | |
| Column label | Description |
| GeneSymbol | Gene symbol: lookup biomaRt (version 2.50.3, Ensembl version 110) |
| Entrez | Entrez ID |
| SignalLead | Lead variant of isolated signal |
| Variant | Chromosome_position_NonEffectAllele_EffectAllele |
| NEA | Non-effect allele |
| EA | Effect allele |
| EAF | Effect allele frequency |
| Beta | Effect size of association between variant and gene |
| SE | Standard error |
| PVAL | p-value of association between variant and gene |
| N | Sample size for variant |
| Studies | Studies with gene expressed. 1=Germany (145), 2=Schadt (555), 3=Merck (322), 4 = BLP (161) |
| ENSG | Ensembl ID for gene: lookup biomaRt (version 2.50.3, Ensembl version 110) |
| Gene_Biotype | Gene Biotype: lookup biomaRt (version 2.50.3, Ensembl version 110) |
| Files for download: | |
| Description | Isolated conditional summary statistics for signficant signals – all results by chromosome |
| Filename | Liver_eQTL_IsolatedSignals_byChr.tar.gz |
| Size | 1.1 GB |
| Date | 3/4/24 |